Matt develops Cataracts after he and Foggy split. They're severe, and completely cloud his pupil, leaving him blind if he wasn't before.
Nobody bothers to tell him he's developed cataracts, because they think that's part of his blindness.
Cue ghostly unnerving stares, and even more reason for him to keep his glasses on.

+ Jessica gives him a ghost pun, which he doesn't understand at all
+++ People struggle or misidentify his eye colour which hurts his self esteem because wow, do his eyes really freak people out that much
++++++ Foggy or Karen groan at him and ask if he got another chemical spill in his eyes, leaving him super confused and self conscious