In a world where it is commonly believed that Matt is indeed a supernatural creature, Frank Castle still loses his family. Matt has 'granted' some prayers/vengeance/wishes because he could hear them. Some how it come to light that the Irish/Dogs/Cartel invoked the Devil/prayed for his help taking down his family. Frank adds it to his list.

After shooting him in the head with no damage and his escape from his interrogation (still managing to kick a whole gang's ass) Frank has come to two conclusions. The Devil is indeed real and he's taken possession of a blind man named Matt Murdock.

So he decides to see a priest to help exorcise him...